What is Liposarcoma?
What is Liposarcoma? Liposarcoma is a malignancy or cancer in fat tissue. Liposarcoma can occur in fat tissue in any part of the body, but most often occurs in fatty tissue at the back of the knee, thigh, groin, buttocks, or retroperitoneum (space behind the abdominal cavity). Liposarcoma is one type of soft tissue sarcoma, and is a rare type of malignancy.
Some patients are aware of a liposarcoma tumor after a hard injury or collision (trauma) in certain body parts. However, it is not known for certain whether trauma has a relationship with liposarcoma. The exact cause of liposarcoma itself is not known for certain until now.
Liposarcomas can be experienced by both men and women regardless of age, but this cancer is more common in adults aged between 40-60 years. Treatment of liposarcoma is by lifting or killing cancer cells in several ways, such as surgery and radiotherapy.
There are five types of liposarcoma that are known in the medical world, namely:
- Well-differentiated liposarcoma. It is the most common type of liposarcoma. The growth of this tumor is quite slow and painless.
- Myxoid liposarcoma. Is the second type of liposarkoma most. About 3 out of 10 cases of liposarcoma are of this type.
- Round cell liposarcoma. The most common type found in children and adolescents.
- Pleomorphic liposarcoma. The most rare type of liposarcoma, very aggressive and spread rapidly.
- Dedifferentiated liposarcoma. Is the type of liposarcoma with the highest levels of malignancy. The risk of spreading (metastasis) is very high and rapid.
Symptoms of Liposarcoma
Most patients are unaware of this malignancy, because the symptoms are unclear or even absent. Usually the new patient is aware when the condition of the disease has worsened and symptoms appear, such as:
- Swelling in certain body parts.
- Movement in the legs is limited.
- Abdominal pain, nausea, and vomiting.
- Varicose veins (if any) become larger.
- Feel tired.
- Numbness in an abnormal location.
Some checks that can be done to diagnose liposarcoma, among them:
- Imaging. Through X-rays, CT Scan, and MRI. This examination will provide a clear picture of the size and level of malignancy of liposarcoma.
- Biopsy. Takes some of the problematic tissue as a sample for pathology examination.
- Laboratory examination. Laboratory tests generally include immunohistochemistry, cytogenetic analysis, and molecular genetic testing.
There are three types of treatment that can be done to overcome liposarkoma, namely:
- Operation. This procedure is performed with the aim of removing cancer cells in body tissues. If possible, the doctor will remove all the liposarcomas or as many of the malignant malignancies as possible. Amputation can also be considered if the cancer that grows on the foot is severe enough and is at risk of causing complications. However, it is rare.
- Radiotherapy. Performed with the help of X-rays, aims to kill cancer cells. Radiation can be performed both before and after the patient undergoes surgery.
- Chemotherapy. With the provision of drugs that can kill cancer cells. However, not all types of liposarcoma can be treated with drugs, so a correct diagnosis in determining the type of liposarcoma will largely determine the success of treatment.