Symptoms of Lou Gehrigs Disease
Early signs and symptoms of Lou Gehrig disease usually begin from the hands, then to the legs, and spread to other parts of the body. Symptoms consist of:
- Hands feel weak and often drop the goods.
- Weak on the legs and feet, so often fall or trip.
- Difficult to hold your head.
- Difficult to maintain body position.
- Speech is not clear.
- Difficult to swallow.
- Difficult to walk and perform normal daily activities.
- The Cause of Lou Gehrig’s Disease
Not yet known exactly what causes damage to nerve cells in this disease. Approximately 10 percent of cases occur, found a genetic mutation that causes the formation of a protein that is damaging nerve cells.
There are several other factors that are also suspected to be the cause of cell damage in ALS, including:
- Excess glutamate. Glutamate is a chemical that acts as a sender of messages to or from the brain and nerves. However, if there is accumulation of glutamate around the nerve cells can cause damage to the nerves.
- Immune system disorders. Under certain conditions, one’s immune system actually attacks healthy cells in the body and causes damage to nerve cells.
- Disorders of the mitochondria. Mitochondria are the places of energy formation in cells. Disorders in this energy determination can damage nerve cells, as well as accelerate the deterioration of diseases that may be caused by other factors.
- Oxidative stress. Excessive free radical levels will cause oxidative stress, and cause damage to various body cells.