Epidermolysis Bullosa Causes
Epidermolysis Bullosa Causes

5 Most Common to Epidermolysis Bullosa Causes in Humans

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Epidermolysis Bullosa Causes in Humans

A person suffering from Epidermolysis Bullosa Causes does not have a binding protein between the upper and lower skin layers causing the upper and lower skin to rub against. It causes the skin becomes brittle and easily peeled, though only rubbed, triggering blisters and wounds. This condition is due to mutations in at least 18 types of genes with 300 variations that have been found. The variation then classifies the Epidermolysis Bullosa into several types such as:

  1. Epidermolysis bullosa simplex – Caused by defects in genes that produce keratin, causing blisters to appear in the epidermis, usually on the soles of the feet and palms. This condition generally develops when born or the first few years of the baby’s age and allegedly comes from the father or mother. Epidermolysis Bullosa simplex is more common than other types.
  2. Dystrophic epidermolysis of bony – Caused by a defect in the collagen-producing gene, a gene that unifies the skin properly. Symptoms may vary from mild to severe. This condition is generally known at birth or in childhood.
  3. Junctional epidermolysis bullosa – Caused by defects in genes that produce fibers such as yarn that bind the epidermis with basal membranes, causing separation of tissue and blisters that appear in the inner skin layer. This condition is usually severe and immediately realized when the baby is born, triggering symptoms of crying due to blisters and the formation of scar tissue in the vocal cords. Both parents allegedly inherited this gene to the child, although both did not show symptoms of Epidermolysis Bullosa.
  4. Kindler Syndrome – In this condition, blisters develop throughout the skin layer, causing discoloration of sun exposed skin and generally appearing at birth or shortly after birth. This condition is rare and will usually improve or disappear over time. Kindler’s syndrome is a recessive type of Epidermolysis Bullosa.
  5. Epidermolysis bullosa acquisita – This rare condition is different from other Epidermolysis Bullosa because it is not a hereditary disease but due to a disorder or disorder of the immune system that attacks the body’s own healthy tissue. Blistering skin usually appears in the hands, feet, and mucous membranes, or inner skin layers.

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